Pain and Distress Associated with Polyclonal Antibody Production: Discussion and Recommendations

A group of international experts participated in a roundtable discussion at a scientifically-based meeting held by The HSUS in August 2002 and considered several animal welfare-related aspects of Polyclonal antibody (Pab) production, including determination of appropriate adjuvants, optimal volume of adjuvant per species, optimal route of immunization, use of booster injections, available alternatives, and measurement of animal welfare.

This manuscript discusses the experts’ recommendations, which are based on their experiences, as well as published literature on these topics. Participants in the workshop recognize that insufficient attention has been paid to animal welfare aspects of Pab production; therefore, The HSUS is widely distributing this manuscript in an attempt to increase attention to the alleviation of pain and distress associated with Pab production.

To view the full manuscript, download the PDF. Please feel free to contact us at ari@hsus.org if you have feedback or questions, or would like additional copies.